CRISPR/Cas9 mouse model reveals cellular function changes that drive rare disease
A CRISPR/Cas9 mouse model has shown how mutations that cause a rare disease affect cellular function, shedding light on how to monitor and treat the condition in the process. Read More
Correlation of enzyme to survival reveals potential target for metastatic solid tumors
The enzyme lysyl hydroxylase 1 (LH1) promotes the migration and metastasis of solid tumor cells and is associated with shorter survival, according to a recent study published in Molecular Cancer. Read More
Illumina, Myriad Genetics provide U.S. access to HRD research test
Illumina and Myriad Genetics have expanded a strategic partnership aimed at broadening access to oncology homologous recombination deficiency (HRD) testing for oncology. Read More
At SLAS 2023, companies showcase, launch advanced automation and screening technologies
At the Society for Laboratory Automation and Screening (SLAS) 2023 International Conference and Exhibition, being held in San Diego from February 25 to March 1, numerous firms have announced that they are showcasing emerging technologies for advanced life science applications. Read More
Agilent Technologies announces integrated on-deck thermal cycler for NGS platform
Agilent Technologies on Monday announced the release of an on-deck thermal cycler (ODTC) that integrates with its Bravo NGS automated liquid handling platform. Read More
Beckman Coulter, Sciex collaborate on high-throughput screening workflows
Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies. Read More
Analysis of genome-wide methylomic variations reveal epigenetic changes in Alzheimer’s brains
DNA methylation affects gene and protein co-expression networks associated with Alzheimer’s disease and offers a novel way to treat the condition, according to new research. Read More
Discovery of telomere-encoded proteins spurs work on blood test for biological age
The discovery that telomeres, previously considered noncoding DNA, are involved in the production of two proteins is spurring interest in the development of a blood test for biological age. Read More
Algorithm predicts success of next-generation CRISPR edits, advancing push to treat genetic diseases
A machine learning algorithm has predicted the chances of successfully inserting a gene-edited sequence of DNA into a cell using a next-generation CRISPR-Cas9 approach. Read More
Software assembles complete genome sequences on-demand
National Institutes of Health (NIH) researchers have released an innovative software tool that makes assembling complete genome sequences from a variety of species more affordable and accessible. The study, published February 16 in Nature Biotechnology, describes the software, called Verkko -- “network” in Finnish. Read More
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