Scientists seek HIV cure by transplanting stem cells to monkeys
Scientists are seeking a cure for HIV via stem cell transplants on monkeys. Their research, published Thursday in the journal Immunity, describes the process by which two of four non-human primates were cured of HIV following stem cell transplantation. Read More
Biomarkers in a study predict stem cell transplant risks
Risk biomarkers uncovered in a recent study may help medical staff predict which donor stem cell transplant patients are likely to develop a potentially deadly side effect called sinusoidal obstruction syndrome (SOS). Read More
Medical records link vaccination against COVID-19 to reduced risk of non-respiratory symptoms
Fully vaccinated individuals had a lower risk of dying or developing some non-respiratory symptoms than people without protection against COVID-19 during the Delta and Omicron waves, a retrospective review of medical records has found. Read More
FDA approves first topical gene therapy for treatment of wounds in patients with dystrophic epidermolysis bullosa
The U.S. Food and Drug Administration (FDA) said on Friday it has approved Vyjuvek, a herpes-simplex virus type 1 (HSV-1) vector-based gene therapy, for the treatment of wounds in patients six months of age and older with dystrophic epidermolysis bullosa (DEB) and with mutations in the collagen type VII alpha 1 chain (COL7A1) gene. Read More
Revvity, AstraZeneca ink license agreement for next-gen base editing tech
Revvity this week announced a nonexclusive license agreement with AstraZeneca for the technology underlying a next-generation modular gene editing platform. Read More
Alzheimer’s disease and modifiable risk factors: Genetic associations revealed
A genetic association study comparing participants with Alzheimer’s disease and control participants without Alzheimer’s disease found novel genetic associations between high high-density lipoprotein (HDL) cholesterol concentrations and high systolic blood pressure and a higher risk of Alzheimer’s disease. Read More
Boundless Bio closes $100 million Series C financing to advance precision oncology therapies
Next-generation precision oncology company Boundless Bio on Tuesday announced the closing of its $100 million Series C financing, which will be used to advance the clinical development of its BBI-355 extrachromosomal DNA-directed oncology therapy. Read More
Clinical trial begins for universal flu vaccine candidate
Researchers at NIH’s National Institute of Allergy and Infectious Diseases (NIAIDs) have developed an experimental universal influenza vaccine. Read More
Biomarker predicts response to chemo-immunotherapy in lung cancer patients
Researchers have found a biomarker that provides an early indication of whether a patient is responding to chemo-immunotherapy. Read More
Genetic variant protects against Alzheimer's disease
For many years, researchers followed a patient who, despite being genetically predisposed to develop early-onset Alzheimer’s disease, beat the odds. Their research, published Monday in Nature Medicine, led to the discovery of a new genetic variant that provides protection from Alzheimer’s disease, a pathway for resilience to dementia, and the identification of a brain region to target with therapeutics. Read More
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