Scientists use bioinformatics to investigate origin of SARS-CoV-2
While many scientists urgently work toward developing successful therapies to fight the COVID-19 pandemic, some are looking in the opposite direction: to where SARS-CoV-2 came from. A new report published in the Journal of Proteome Research suggests that while bats are a likely natural reservoir, an intermediate host is probable. Read More
While many scientists urgently work toward developing successful therapies to fight the COVID-19 pandemic, some are looking in the opposite direction: to where SARS-CoV-2 came from. A new report published in the Journal of Proteome Research suggests that while bats are a likely natural reservoir, an intermediate host is probable. Read More
Controversy hits Gilead over orphan status for COVID-19 drug
Gilead Sciences has rescinded its request for orphan drug status for an experimental drug for treating COVID-19 just two days after getting approval from the U.S. Food and Drug Administration. The company had been hit with criticism that the approval would block other COVID-19 drugs from reaching the market. Read More
Gilead Sciences has rescinded its request for orphan drug status for an experimental drug for treating COVID-19 just two days after getting approval from the U.S. Food and Drug Administration. The company had been hit with criticism that the approval would block other COVID-19 drugs from reaching the market. Read More
Researchers explore mutations to improve drug design
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. Researchers explored how evolution impacted the mutation of these pathogens, and their findings could lead to the development of evolutionarily designed drugs. The results were published March 24 in Cell Reports. Read More
Drug resistance is a common challenge when designing therapeutics for cancers or diseases originating from bacteria or viruses. Researchers explored how evolution impacted the mutation of these pathogens, and their findings could lead to the development of evolutionarily designed drugs. The results were published March 24 in Cell Reports. Read More
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools. Read More
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools. Read More
Systems-based analysis helps researchers understand cell migration
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process. Read More
An international team of researchers has developed a unique library to study the regulation of the cytoskeleton in space and time. The work, published in Nature Cell Biology on March 23, takes a systems-based approach to gain an overview of this process. Read More
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies. Read More
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies. Read More
Cryo-EM sheds light on ion channel regulation
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications. Read More
A long-standing hypothesis about the regulation of ion channels has been confirmed by cryoelectron microscopy (cryo-EM) imaging. The research presented in Nature on March 18 advances the basic understanding of key cellular processes that can be leveraged for a number of therapeutic and research applications. Read More
Comparative genomics confirms natural development of SARS-CoV-2
The available genetic data on SARS-CoV-2 indicate that it is not derived from any previously known virus, suggesting that it originated from either natural selection in an animal host or humans following zoonotic transfer. This analysis, presented in Nature Medicine on March 17, provides evidence for the natural evolution of this novel coronavirus amid claims of manufactured origins. Read More
The available genetic data on SARS-CoV-2 indicate that it is not derived from any previously known virus, suggesting that it originated from either natural selection in an animal host or humans following zoonotic transfer. This analysis, presented in Nature Medicine on March 17, provides evidence for the natural evolution of this novel coronavirus amid claims of manufactured origins. Read More
Researchers make sweet music with protein design technique
What does protein design have to do with music theory? A group of researchers from Massachusetts Institute of Technology saw commonalities between the two and designed a technique based on sonification that translates protein structures into musical scores as part of their effort to design new proteins. The details were published in APL Bioengineering on March 17. Read More
What does protein design have to do with music theory? A group of researchers from Massachusetts Institute of Technology saw commonalities between the two and designed a technique based on sonification that translates protein structures into musical scores as part of their effort to design new proteins. The details were published in APL Bioengineering on March 17. Read More
New biocompatible microparticles created with heat, light
A new simple and scalable protein-processing technique based on temperature-sensitive phase changes creates unique microarchitectures within microparticles for use in drug delivery and other bioengineering applications, according to a study published in Nature Communications on March 12. Read More
A new simple and scalable protein-processing technique based on temperature-sensitive phase changes creates unique microarchitectures within microparticles for use in drug delivery and other bioengineering applications, according to a study published in Nature Communications on March 12. Read More
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