Genomics
Blackstone, Intellia, Cellex to launch company addressing limitations of cell therapies
Blackstone Life Sciences has committed $250 million toward the launch of a new autologous and allogeneic universal chimeric antigen receptor T-cell therapy company. Also taking part in the launch are Intellia Therapeutics and Cellex Cell Professionals, the parent company of GEMoaB, a clinical-stage cell therapy company. Read More
Sciex releases new LC-MS device for low-level metabolite detection
Sciex has announced the release of ZenoTOF 7600, a new liquid chromatography-mass spectrometry (LC-MS)/MS instrument for low-level metabolite detection. Read More
Danaher to acquire Aldevron in deal valued at $9.6B
Danaher announced it has signed a deal to buy DNA and messenger RNA manufacturer Aldevron for approximately $9.6 billion. Aldevron will operate as a standalone company in Danaher's Life Sciences business segment and is expected to boost Danaher's activities in genomic medicine. Read More
DNA Script launches benchtop DNA printer
DNA Script has launched Syntax, a benchtop DNA printer designed for molecular biology and genomics applications. The printer is designed to enable onsite synthesis of DNA oligonucleotides for use in genomics workflows. Read More
How one mammalian DNA polymerase challenges the central dogma of biology
New research demonstrates how an unusual mammalian DNA polymerase can facilitate the conversion of RNA into DNA -- the opposite of normal polymerase function. The data, published in Science Advances on June 11, could challenge the central dogma of molecular biology that states that DNA makes RNA, which in turn makes proteins. Read More
NIH initiative tackles structural racism in biomedical research
A new framework to tackle structural racism was introduced by the U.S. National Institutes of Health (NIH) in a commentary published in the journal Cell on June 10. The initiative is an ambitious effort by the NIH to spur widespread, systematic changes across the biomedical research enterprise. Read More
How spatial biology can impact clinical translational research
Building on the success of single-cell technologies, 10X Genomics' Michael Schnall-Levin, PhD, discusses with ScienceBoard.net how the company entered the spatial biology field and how it continues to support the advancement of various clinical translational research efforts. Read More
New study untangles how proteins ensure efficient DNA repair
Scientists have untangled the function of proteins that block normal DNA repair processes and may permit unwanted cancer cell growth. New research published in Molecular Cell on June 7 details how the XRCC1 molecular scaffold protein works in tandem with the poly(ADP-ribose) polymerase DNA break-detection protein to ensure that genetic errors are efficiently corrected. Read More
Waters debuts mass spectrometer with MRT technology
Waters has introduced its next-generation Select Series multireflecting time-of-flight (MRT) mass spectrometer. The new system is designed to provide high-quality resolution at fast speeds to improve the clarity of molecular structures and their location in tissues for applications in spatial omics. Read More
A new way to account for evolution in engineered biological systems
A defining characteristic of biology is that life evolves. Traditional biological engineering views an engineered product as a final destination in the design process. However, the authors of a perspective piece published in Nature Communications on June 7 believe that a new perspective is needed for engineering of biological systems -- one that takes into consideration how a biosystem will continue to evolve over time. Read More
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