Gene therapy tackles 2 rare childhood diseases 2 different ways
Two new studies point to the efficient use of gene therapy to treat deadly childhood genetic diseases. The first study used direct gene therapy infusion to treat a rare neurodevelopmental disorder, while the second study used prenatal base editing in mouse models as proof of concept for the treatment of genetic diseases. These vastly different approaches show the promise of gene therapy for a variety of devastating diseases. Read More
Strateos launches hybrid SmartLab software platform
Strateos has launched SmartLab, a modular cloud-based software platform designed to assist life science research organizations in connecting onsite research and development labs with remote-controlled facilities. Read More
Machine learning helps scientists map the mammalian immune system
The use of advanced machine-learning software has led to the identification of hundreds of new genes that likely affect the working immune system, according to findings from a study published recently in the Proceedings of the National Academy of Sciences of the United States of America. Read More
BD launches new digital marketplace for flow cytometry
Becton Dickinson (BD) has launched bdbiosciences.com, an updated digital marketplace for flow cytometry. The new website provides an enhanced online purchasing experience for flow cytometry users and their procurement teams. Read More
Nvidia launches Cambridge-1 AI supercomputer to spark life sciences research
Graphics processing unit technology developer Nvidia has launched an artificial intelligence (AI)-powered supercomputer in the U.K. that enables researchers in digital biology and genomics. Read More
Innovation in single-cell sequencing unlocks 10x more data from each cell
A new single-cell sequencing method yields at least 10 times more data for each individual cell compared to previous techniques. The method, published in Nature Biotechnology on July 5, may help cancer researchers uncover new insights into the biological underpinnings of cancer such as drug resistance. Read More
Algorithm expands what scientists can uncover from individual cells
A new software tool can help researchers further utilize single-cell RNA sequencing data to learn more about individual cells by incorporating biologically relevant data into the analysis. The machine-learning algorithm, detailed in Genome Research on June 30, can be used to predict which transcription factors are most active in individual cells. Read More
Oncolytic viruses move closer to becoming effective cancer therapies
Scientists are identifying key factors that aid in the effectiveness of oncolytic viruses during the treatment of cancers, which could lead to better immunotherapies and inform clinicians which patients might benefit from the treatment. Findings from a June 22 Nature Communications article point to the clinical relevance and underlying mechanisms of a novel anticancer treatment. Read More
Twist acquires iGenomX for $35M
Twist Bioscience has acquired next-generation sequencing library preparation developer iGenomX for $35 million. The deal gives Twist a leg up in the shift from genotyping with static microarray platforms to using sequencing workflows. Read More
Intellia, Regeneron highlight clinical results for CRISPR-Cas9 gene therapy
Intellia Therapeutics and Regeneron Pharmaceuticals have announced positive interim data from an ongoing phase I study of their in vivo candidate, NTLA-2001, as a single-dose treatment for transthyretin amyloidosis. The interim results support the clinical efficacy and safety of in vivo CRISPR genome editing therapy in humans. Read More
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