Mayo Clinic, National Resilience to create center for biomanufacturing regenerative technologies
August 16, 2022 -- The Mayo Clinic and biotech company National Resilience have announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions, with a focus on therapies derived from biologics for use in medicines. Read More
Discovery of widespread DNA damage in stem cell lines spurs call for pre-use sequencing
August 12, 2022 -- More than 70% of stem cell lines derived from human skin cells have damage to their DNA that could compromise their use in research and cell-based therapies, according to a study published August 11 in Nature Genetics. Read More
Timothy Hunt to take helm of ARM as new CEO
August 11, 2022 -- The Alliance for Regenerative Medicine (ARM) has announced that Timothy Hunt will succeed Janet Lambert as chief executive officer (CEO) of the Washington, DC-based advocacy organization, which represents the cell and gene therapy industry. Read More
CRISPR-Cas9 gene editing can give rise to cell toxicity, genomic instability: study
August 9, 2022 -- Gene editing using CRISPR-Cas9 can lead to cell toxicity and genome instability depending on the targeted spot of the human genome, according to a new study by researchers at the Institute for Research in Biomedicine Barcelona. Read More
New technique could enable production of generic CAR T cells at scale
August 4, 2022 -- A Boston Children’s Hospital lab has developed a new method that could make chimeric antigen receptor (CAR) T-cell therapy more widely available using induced pluripotent stem cells to develop mature immune cells. Read More
Gene therapy shows promise in treating ALS in rodent models
August 2, 2022 -- A gene therapy, patented through the University of California, San Diego and the Department of Veterans Affairs measurably delayed disease onset in humanized mouse and rat models of familial amyotrophic lateral sclerosis (ALS). Read More
Scientists win $36.5M for cardiac gene editing therapy
August 1, 2022 -- An international team won 30 million pounds ($36.5 million U.S.) to develop cures for inherited heart muscle diseases that use ultra-precise gene therapy technologies to edit or silence the faulty genes that cause the conditions. Read More
Linus survey finds top two techniques or applications in life sciences R&D
July 29, 2022 -- A new survey of scientists finds that the top two techniques or applications in life sciences research and development (R&D) are CRISPR/cell-line engineering and artificial intelligence/machine learning-enabled bioinformatics when it comes to driving scientific advancements. Read More
Genes explain the effects of psychedelic drugs
July 28, 2022 -- Not everyone has the same response to psychedelic drugs and North Carolina researchers have figured out why -- seven genetic variants of one serotonin receptor greatly impact a certain serotonin receptor’s structure and function. Read More
CRISPR-based study identifies lung proteins that promote, protect against SARS-CoV-2 infections
July 27, 2022 -- A study led by University of California, Berkeley researchers has identified specific proteins within the human body that can either promote SARS-CoV-2 infections or protect against them, a discovery they contend could lead to new antiviral therapies. Read More
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