What to do when genetic tests reveal links to cardiovascular disease: Scientific statement
Increased use of genetic testing means that people may discover they have an incidentally-found genetic abnormality, or gene variant, associated with cardiovascular disease (CVD), according to a scientific statement published Monday in the American Heart Association journal Circulation: Genomic and Precision Medicine. Read More
Bile salt analog prevents C. diff infection in mice, advancing work to stop killer bacterium
A bile salt analog prevented Clostridioides difficile infection (CDI) in mice, pointing to a potential way to minimize the impact of a bacterium that kills 20,000 people a year. Read More
Impact of circadian rhythms on cellular functions points to better ways to treat cancer
Knowledge of how circadian rhythms affect cellular functions involved in the formation and progression of tumors could improve cancer treatment, according to a study published in Trends in Cell Biology. Read More
Immune system power may lessen reliance on antibiotics for tuberculosis
Francis Crick Institute researchers have found that the body’s natural process of removing old and damaged cell parts may be an essential part of tackling infections like tuberculosis (TB) that take hold within cells. They hypothesized that harnessing this process might present alternatives to antibiotics or improve antibiotic use. Their study was published in Nature Microbiology on Friday -- World TB Day. Read More
Shared genetic markers linked with substance use disorders
By combing through genomic data from more than one million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. Read More
RNA-seq analysis links protein to spread of pancreatic cancer, reveals potential drug target
An analysis of 400 pancreatic cancer tumor samples has linked a protein that controls RNA processing to the formation of metastases, suggesting that it may be possible to delay the spread of the cancer. Read More
A*STAR partners with startup to create diabetes cell therapies tailored to Asian patients
BetaLife has acquired the rights to human induced pluripotent stem cell (iPSC) technology from Singapore’s Agency for Science, Technology, and Research (A*STAR) for use in the treatment of diabetes. Read More
Neutrophil culprits cause pancreatic cancer treatment resistance
Researchers have discovered how immature neutrophils -- white blood cells that are an important part of the immune system -- are hijacked by pancreatic cancers to drive treatment resistance. The study, published Wednesday in Cancer Discovery, may facilitate new pancreatic cancer treatment avenues. Read More
Contagious fungal infections increase dramatically
According to national surveillance data, candidiasis cases caused by Candida auris, a highly infectious fungus, rose drastically between 2019 and 2021, reflecting increased transmission. Read More
Gestational diabetes rise linked to screening practices
A Canadian Medical Association Journal study published Monday found that although gestational diabetes is reportedly on the rise, changes in screening practices may largely explain the increase. Read More
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