Immunology
Genomics profiling reveals how Zika infects immune cells, suggests antiviral target
A genomics profiling method has revealed how the Zika virus infects human dendritic cells, pointing to a potential target for therapeutic suppression of the pathogen. Read More
Inhibiting white blood cell enzyme reduces lung metastases in mice: study
Researchers at The Wistar Institute and Jubilant Therapeutics have found an enzyme in neutrophils that promotes tumor growth and metastasis, pointing to a new way to treat cancers. Read More
Stanford platform improves hunt for antigens that trigger strong immune responses
Researchers at Stanford University have developed a method for making faster, more accurate predictions of which antigens will trigger a strong immune response. Their work could help scientists develop more effective cancer immunotherapies. Read More
Blocking key enzyme boosts anticancer T-cell responses, resistance to immunosuppression
Blocking a key enzyme boosts anticancer T-cell responses and resistance to immunosuppression, according to a mice study from LSU Health New Orleans published August 26 in Frontiers in Immunology. Read More
Oncolytic virotherapy, immunotherapy combo shows promise for treatment-resistant cancers
A combination of oncolytic virotherapy, a technique using cancer-fighting viruses, acting in concert with immunotherapy shows promise for treatment-resistant cancers, according to new research. Read More
CRISPR reveals way to enhance the function, persistence of CAR T-cell therapies
The use of CRISPR knockout screens have uncovered a new regulator of immunity that could enhance the function and persistence of anti-cancer T-cell therapies, according to a study published on August 24 in the journal Nature. Read More
Localized delivery of IL-2 by drug-producing cells eradicates cancer in mice
Implanting beads loaded with cytokine-producing cells eradicates advanced-stage mesothelioma tumors in mice, according to a study published on August 22 in Clinical Cancer Research. Read More
Antiviral-antibody combination improves influenza outcomes in mice
Researchers at McMaster University found in a mouse study that combining a class of well-known antiviral drugs and neutralizing antibodies was more effective than either approach alone, which they contend could be used to treat seasonal influenza and help prevent the next flu pandemic. Read More
Hormone restrains growth of liver tumors in mice, offers therapeutic targets
University of Michigan researchers have identified in a mouse study a hormone -- neuregulin 4 -- that serves as a checkpoint for the progression of nonalcoholic steatohepatitis and appears to have potential as a treatment for hepatocellular carcinoma, the most common type of primary liver cancer. Read More
Synthesis breakthrough opens door to development of natural product as cancer therapy
Princeton University scientists have halved the number of steps needed to synthesize pleurotin, setting the stage for work to realize the anticancer and antibiotic potential of the molecule. Read More
Conferences
Laboratory Products Association Annual Meeting
October 1-4
Scottsdale, Arizona United States
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
IDWeek 2022
October 19-23
District of Columbia United States
American Society of Human Genetics Annual Meeting
October 25-29
Los Angeles, California United States
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