Drug Discovery & Development
Analysis of nanoparticles, cancer cells could aid development of nanoparticle-based drugs
Researchers have identified biomarkers that predict whether different types of cancer cells will take up specific nanoparticles, potentially helping to overcome some obstacles to the development of nanoparticle-based drugs. Read More
Lessons from Operation Warp Speed could benefit future drug discovery
What lessons can the biotech industry learn from Operation Warp Speed? In an interview with ScienceBoard.net, Debrah Thompson, PhD, of HTG Molecular Diagnostics, discusses how the success of the COVID-19 vaccine rollout could benefit the drug discovery process going forward. Read More
Repetitive DNA linked to cancer formation in study of replication process
Researchers have discovered that noncoding "junk" DNA could potentially contribute to the development of cancer. Repetitive DNA sequences can cause replication to stall, triggering a response that is similar to the one induced by DNA damage, according to a study published July 19 in Nature Communications. Read More
Current COVID-19 boosters provide protections against serious infection: study
Despite the evolution of the SARS-CoV-2 pandemic coronavirus, a new laboratory study conducted by a team of international researchers suggests current vaccine boosters may elicit sufficient immune protection against severe omicron-induced COVID-19 disease. Read More
RNA molecules identified as potential ‘common driver’ of cancer progression
Moffitt Cancer Center researchers have challenged the widely held view that protein structure and function are the key drivers of cancer development. Their study found competitive endogenous RNA drive melanoma growth and metastasis by blocking the antitumor activity of other molecules. Read More
Cardiac mouse model shows role white blood cells play in arrhythmia
Feeding mice a diet lacking in potassium induces ventricular tachycardia, a rapid heartbeat, enabling researchers to study how different white blood cell subclasses influence heart rhythms. Read More
Protein crystallography links rigid antibody hinges to increased anticancer activity
Researchers at the University of Southampton have gained new insight into the key properties of an antibody needed to fight off cancer using protein crystallography, revealing that the flexibility of the hinge between the arms of IgG2 antibodies affects the anticancer effects triggered by the molecules. Read More
Single-cell sequencing finds subset of CAR T cells that drive anticancer effects
A small subset of the CAR T cells prepared for therapy produce most of the anticancer activity, suggesting it may be possible to improve the treatment, according to a study published in the journal Cancer Discovery. Read More
Plant-microbe biology study uncovers trigger for tumor growth in humans
Targeting the plasminogen-apple-nematode domain can block cell proliferation, pointing to the potential to treat certain cancers, according to a paper published in the journal Communications Biology. Read More
NIH-funded research yields promising results for potential universal flu vaccines
A study funded by the National Institutes of Health (NIH) has shown that a new universal flu vaccine offers broad protection against different strains and subtypes of influenza A virus infections. Read More
Conferences
Laboratory Products Association Annual Meeting
October 1-4
Scottsdale, Arizona United States
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
IDWeek 2022
October 19-23
District of Columbia United States
American Society of Human Genetics Annual Meeting
October 25-29
Los Angeles, California United States
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