New drug turns COVID-19 virus against itself in animal models
A Scripps Research team showed that NMT5, a variation of a previously approved drug, can cause the COVID-19 virus to block infection in animals and bring about its own demise. Read More
SARS-CoV-2 mimics could make COVID-19 vaccine research safer, quicker
Viruslike particles, molecular mimics that look and act like SARS-CoV-2 without being infectious, are providing new tools against COVID-19 -- the disease caused by the virus. Read More
Mount Sinai scientists unlock secrets of key SARS-CoV-2 enzyme
Mount Sinai researchers have produced a high-resolution crystal structure of an enzyme that is essential to the survival of SARS-CoV-2. The finding could lead to more antivirals to combat current and future coronaviruses, they added. Read More
Antiviral therapy blocks COVID-19 transmission in hamsters: study
Researchers at Gladstone Institutes have shown that a new single-dose intranasal, antiviral treatment for SARS-CoV-2 infection decreases viral shedding and limits transmission of the virus in hamsters. Read More
Harvard’s Wyss Institute spins out protein detection technology to create Spear Bio
The Wyss Institute for Biologically Inspired Engineering at Harvard University has licensed technology for detecting proteins in small patient samples to a newly formed startup. Read More
Key vulnerability discovered across all major SARS-CoV-2 variants
Researchers at the University of British Columbia have discovered a “weak spot” across all major variants of the SARS-CoV-2 virus, including the recently emerged BA.1 and BA.2 omicron subvariants, using cryo-electron microscopy to reveal the atomic-level structure of the vulnerability on the spike protein. Read More
Antiviral-antibody combination improves influenza outcomes in mice
Researchers at McMaster University found in a mouse study that combining a class of well-known antiviral drugs and neutralizing antibodies was more effective than either approach alone, which they contend could be used to treat seasonal influenza and help prevent the next flu pandemic. Read More
New antibody neutralizes all known SARS-CoV-2 variants: study
An antibody developed at Boston Children’s Hospital neutralizes all known SARS-CoV-2 variants, including omicron subvariants, which may inform the design of future COVID-19 vaccines. Read More
Timothy Hunt to take helm of ARM as new CEO
The Alliance for Regenerative Medicine (ARM) has announced that Timothy Hunt will succeed Janet Lambert as chief executive officer (CEO) of the Washington, DC-based advocacy organization, which represents the cell and gene therapy industry. Read More
‘Jumping gene’ affects immune system response, helps mice survive virus infections
Australian researchers have learned a particular transposable element, a “jumping gene,” has a profound effect on the immune response to virus infection, at least in mice. Read More
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