Academic CDMOs, like commercial ones, play critical role in CGT sector October 27, 2022 -- The cell and gene therapy (CGT) industry is growing and academic contract development and manufacturing organizations (CDMOs) -- like their larger commercial counterparts -- are playing a critical role in the ecosystem, according to Stuart Curbishley, PhD, head of business and process development at the University of Birmingham’s Advanced Therapies Facility.Read More
Induced pluripotent stem cell technology offers potential treatment for hair loss October 25, 2022 -- Science Advisory Board spoke with Stemson Therapeutics co-founder and CEO Geoff Hamilton earlier this month at the 2022 Cell & Gene Meeting on the Mesa about the preclinical stage cell therapy company's focus on curing hair loss by leveraging the regenerative power of induced pluripotent stem cells.Read More
Cell therapy startup NKILT Therapeutics takes novel approach to targeting leukemia October 24, 2022 -- Biotech startup NKILT Therapeutics is developing a novel approach of engineering natural killer cells to directly target leukemias and solid tumors. Science Advisory Board spoke with Raphaël Ognar, co-founder and CEO of the company earlier this month at the 2022 Cell & Gene Meeting on the Mesa in Carlsbad, CA.Read More
Antion Biosciences takes allogeneic approach to therapies with microRNA technology October 21, 2022 -- Science Advisory Board spoke with Dr. Sven Kili, CEO of Antion Biosciences, at last week’s 2022 Cell & Gene Meeting on the Mesa, where he laid out his vision for where the company is heading and what the industry needs to do to cure diseases with significant unmet medical needs.Read More
CDMO Lonza continues drive to support cell and gene therapy commercial customers October 20, 2022 -- In an interview with Science Advisory Board, Alberto Santagostino, senior vice president and head of cell and gene technologies at Swiss contract development and manufacturing organization (CDMO) Lonza, discussed bluebird bio's two recent U.S. Food and Drug Administration-approved gene therapies.Read More
Low phosphate levels linked with CAR T neurological toxicity October 20, 2022 -- Patients with hypophosphatemia had higher incidences and more severe neurological side effects on chimeric antigen receptor (CAR) T-cell therapy than those with normal blood phosphate levels, according to a study published October 19 in the journal Cancer Immunology Research.Read More
Platform enables precise, efficient delivery of genetic medicines in vivo October 17, 2022 -- Biotech company Homology Medicines is leveraging 15 human hematopoietic stem cell-derived adeno-associated virus vectors to precisely and efficiently deliver genetic medicines in vivo via gene therapy or nuclease-free gene editing modality. CEO Albert Seymour spoke with Science Advisory Board about their platform.Read More
Manufacturing remains big challenge for cell and gene therapy industry October 17, 2022 -- Science Advisory Board spoke with Eric Blair, chief commercial officer for Andelyn Biosciences, at last week’s 2022 Cell & Gene Meeting on the Mesa about the challenges of manufacturing to meet growing demand in the cell and gene therapy industry.Read More