Rice to establish Genetic Design and Engineering Center
Researchers at Rice University have received a five-year, $4 million grant from the Cancer Prevention and Research Institute of Texas to establish a new Genetic Design and Engineering Center. Read More
Researchers create 3D tumor models with cells from patients
Using tissue samples from cancer patients, Israeli researchers have successfully printed an active, viable glioblastoma 3D tumor model. In addition to potential applications in personalized medicine, the achievement promises to speed drug development and increase the chances that developed drugs will succeed in clinical trials. The results were published August 18 in Science Advances. Read More
Heat-controlled CAR T cells show improved cancer-killing ability
By adding a genetic on-off switch to engineered CAR T cells, researchers have developed a remote-controlled system that enables precision invasion of the tumor microenvironment for improved cancer-killing capabilities. The details of the research were published in Nature Biomedical Engineering on August 12. Read More
Researchers call for improved reporting of environmental conditions in cell culture
There is an urgent need to improve the reporting of environmental conditions for mammalian cell culture experiments for biomedical research, according to a comment published in Nature Biomedical Engineering on August 13. Read More
Mirus Bio introduces viral vector manufacturing reagents
Mirus Bio announced an expansion of its TransIT VirusGen platform that is compliant with good manufacturing practices viral vector manufacturing to support cell and gene therapy development, process activities, and commercial production. Read More
New sensor-based test could lead to fast, cheap antibiotic susceptibility testing
Scientists have developed a new method for monitoring bacterial responses to antibiotics that could enable personalized antibiotic therapies. The test uses sensors to reduce time and costs while increasing the portability for antibiotic susceptibility testing of patient samples. The results of the study were published recently in Scientific Reports. Read More
Prime editing shows promise for complex diseases like cystic fibrosis
Researchers have demonstrated that prime editing -- a newer version of CRISPR-Cas9 gene editing -- can be successfully employed to correct gene mutations that cause cystic fibrosis. The new study, which tested the technique in human organoids, was published in Life Science Alliance on August 9. Read More
Microscopic defects of healthy cells affect spread of ovarian cancer cells
Biophysics researchers have applied the concept of topological defects to investigate the spread of ovarian cancer cells. Using an in vitro model, the researchers found that these defects -- or disruptions in the normal cellular layout -- can affect the rate of tumor cell invasion. Their findings were published online in APL Bioengineering on August 3. Read More
Sunlight causes DNA damage associated with melanoma
Unlike other cancers, melanoma results from a chemical reaction that damages DNA and is fueled by sunlight, according to a new study published in Science Advances on July 30. Read More
Cardiac cell protein may be key to preventing heart failure
A protein that controls calcium signaling within heart cells could help prevent chronic heart failure, according to the results of a new study published in Nature Communications on July 28. The findings point to the protein as a therapeutic target for drugs that could alleviate heart failure. Read More
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