New gene writing tech shows promise for large DNA insertions
An international team has developed a new gene writing technology called find cut-and-transfer that is able to make large gene insertions. The approach, published in Nature Communications on December 3, has potential gene editing and gene therapy clinical applications in patients with genetic and oncological diseases who have few treatment options. Read More
Cool imaging measures cells in motion
A new method, which involves cooling living cells at extremely fast speeds, leads to unprecedented preservation of cellular biomolecules in their natural arrangement at the moment of arrest. Details of the technique were published in Science Advances on December 10. Read More
Stem cell model reveals gene expression during development of hypothalamus
Researchers created an in vitro stem cell model of the hypothalamus to study its development over different stages. In doing so, they identified several genes involved with bodily functions associated with the hypothalamus, including disorders related to sleep and reproduction, according to research published November 19 in Nature Communications. Read More
Technology upgrades needed to address future pandemics, GAO report says
Vaccine R&D and manufacturing face many challenges despite the success of COVID-19 vaccines. This is according to a new U.S. Government Accountability Office (GAO) report. Read More
Cellaria launches new tumor modeling platform
Cellaria has launched a new tumor modeling platform that includes a panel of cell culture media for growing cell types, an extracellular neutral collagen matrix, and protocols for testing new drug compounds. Read More
Learning from older drug modalities accelerates viral process development
Andrew Tustian, EngD, director of viral process development at Regeneron Pharmaceuticals, spoke with ScienceBoard.net about accelerating process development for adeno-associated viruses by modifying strategies from older modalities. Read More
End-to-end automation of closed manufacturing can make cell therapies more accessible
BOSTON - Cellares is building a cell manufacturing platform that fully automates and closes the process, according to co-founder and CEO Fabian Gerlinghaus. ScienceBoard.net spoke with Gerlinghaus following a presentation at the Cell and Gene Manufacturing and Commercialization event, which is part of Biotech Week Boston 2021. Read More
Thermo launches AAV production, digital PCR systems
Thermo Fisher Scientific announced that it has launched two new products. The first product is an adeno-associated virus (AAV) production system, while the second is a digital polymerase chain reaction (dPCR) system. Read More
NanoCellect raises $35M for new development
NanoCellect Biomedical has raised $35 million this year in funding rounds to accelerate the company's commercial growth plans and new product development goals. Read More
Researchers figure out how the immune system sparks cell death
Immunologists have discovered how the innate immune system launches a multifaceted attack against invaders through the use of multiple immune sensors. The work was published in Nature on September 1. Read More
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