New sensor-based test could lead to fast, cheap antibiotic susceptibility testing
Scientists have developed a new method for monitoring bacterial responses to antibiotics that could enable personalized antibiotic therapies. The test uses sensors to reduce time and costs while increasing the portability for antibiotic susceptibility testing of patient samples. The results of the study were published recently in Scientific Reports. Read More
Microscopic defects of healthy cells affect spread of ovarian cancer cells
Biophysics researchers have applied the concept of topological defects to investigate the spread of ovarian cancer cells. Using an in vitro model, the researchers found that these defects -- or disruptions in the normal cellular layout -- can affect the rate of tumor cell invasion. Their findings were published online in APL Bioengineering on August 3. Read More
Abcam to purchase BioVision for $340M
Custom antibody developer Abcam plans to purchase biotechnology firm BioVision for $340 million. Read More
Cardiac cell protein may be key to preventing heart failure
A protein that controls calcium signaling within heart cells could help prevent chronic heart failure, according to the results of a new study published in Nature Communications on July 28. The findings point to the protein as a therapeutic target for drugs that could alleviate heart failure. Read More
Cytiva, Pall to invest $1.5B in biomanufacturing over next 2 years
Cytiva and Pall, both Danaher companies, will make major investments in manufacturing capacity and services at 13 sites around the globe supporting life science customers, totaling $1.5 billion over two years. Read More
Bio-Techne launches multiplex spatial genomics assay
Bio-Techne has expanded its RNAscope in situ hybridization technology portfolio with the release of the new RNAscope HiPlex V2 assay for formalin-fixed, paraffin-embedded and fixed and frozen samples for up to 12 targets. Read More
Cells sense repetitive mechanical forces through 'molecular clutch'
A phenomenon known as a "molecular clutch" allows cells in the body to detect the constant mechanical forces they experience, yet the mechanisms for this phenomenon are poorly understood. Now, in a study published recently in Nature Communications, researchers have shown that the frequency of forces can significantly alter the effect on cells. Read More
Cellular programming spurs next-generation cell therapies
Cellular reprogramming of ex vivo cells may offer improvements on first-generation adoptive cell therapies, which have experienced limited clinical success due to complex manufacturing, potential patient rejection, and availability of clinical cell types. Further, in vivo reprogramming may expand on this concept by eliminating the need for manufacture and the risk of immune rejection. Read More
Researchers capture new ribosome structures in motion
Researchers have captured six new structures of the ribosome and its directional movement using single-molecule fluorescence resonance energy transfer and cryogenic electron microscopy. The results were published in Nature on July 7. Read More
Researchers image mouse brain in entirety with multimodal pipeline
Researchers have successfully combined multiple imaging modalities on the same brain tissue to capture the anatomic features of neurons across the entire mouse brain. The pipeline of imaging modalities and results are detailed in NeuroImage. Read More
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