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Senescent neuron discovery in brains opens path for Alzheimer's drug development
Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration.
Single-cell fetal brain profiling uncovers potential ways to treat pediatric tumors
A multinational team of scientists has used single-cell profiling of freshly isolated human fetal tissue to reveal a reference map of the cell states of the most common malignant childhood brain cancer.
Penn researchers create adrenal gland organoid using stem cells
A research team, led by the University of Pennsylvania's School of Veterinary Medicine, has used stem cells to grow an organoid in a petri dish with the characteristics and functions of a human fetal adrenal gland.
Rapidly generated artificial enzymes inhibit COVID-19 infection in preclinical tests
Artificial enzymes targeting the SARS-CoV-2 genome can inhibit viral infection, pointing to a new way to rapidly develop treatments for emerging biological threats such as COVID-19.
Enzyme shown to restore cell volume after exposure to external stressors
Researchers at the University of Pittsburgh and Carnegie Mellon University have shown that with-no-lysine (WNK) kinases activate a "switch" to restore cell volume after exposure to an external stressor, such as high levels of salt or sugar.
New computational method maps architecture of human tissues in unprecedented detail
Weill Cornell Medicine researchers have developed a new computational method to map the architecture of human tissues in unprecedented detail, with the potential to accelerate studies on organ-scale cellular interactions and enable powerful new diagnostic strategies for an array of diseases.
Programmable RNA-sensing technology enables manipulation of specific cell type
Researchers have developed a programmable RNA-sensing technology that triggers the production of a payload protein when it encounters specific cell types, with potential applications in diagnostics and therapeutics.
Challenge to textbook model of GPCR-mediated signaling opens door to new therapies
University of California, San Diego researchers have challenged the textbook model of how G protein-coupled receptors (GPCRs) mediate signaling in a study that could change how drugs against widely pursued targets are developed, including multiple forms of cancer.
Researchers develop way to observe bacteria in 3D environments such as tissues
Hydrogels have enabled Princeton University researchers to see how bacteria grow in 3D environments, enabling them to make unprecedented observations of bacterial colonies in their natural 3D state.
Healing properties of senescent cells raise questions about anti-aging research
University of California, San Francisco researchers have found some senescent cells help to heal damaged tissues, raising questions about the merits of killing them to address age-related diseases.
More Conferences »»
Newly-discovered organelle key to sense of smell
Immune surprise: alarm protein drives inflammation
Study: Menarini’s CellSearch technology effective in measuring and monitoring CTC levels in multiple myeloma
Oxytocin could be the key to neural plasticity: study
NIH awards $1.8M grant to study long-term memory
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