Cancer & Disease Research
NIH funds repurposing of breast cancer drug against glioblastoma
The National Institutes of Health (NIH) is funding research into the repurposing of the breast cancer drug letrozole for use against the most deadly form of brain tumors. Read More
Combination therapy improves survival in mice with deadly glioblastoma
Combining an antidepressant and vascular endothelial growth factor inhibitor improves outcomes in mouse models of a hard-to-treat type of brain cancer, despite neither treatment being efficacious as a single agent, according to new research. Read More
Researchers further understanding of how circadian clock helps brain recover after injury
Children’s National Hospital researchers have found that a relatively newly discovered type of brain cell -- known as NG2-glia -- also follows a circadian rhythm, findings that potentially open new paths of investigation for the development of future traumatic brain injury therapies. Read More
Hormone therapy improves cognitive function in Down syndrome in small pilot study
Subcutaneous doses of gonadotropin-releasing hormone, a master molecule that controls reproduction, may improve cognitive function in men with Down syndrome, according to results of a small pilot study built on research in mice. Read More
Multiomics analysis reveals potential opportunity for early intervention in Alzheimer’s
A gene that carries a strong risk for Alzheimer’s disease drives changes in the brain’s blood vessels that lead to problems in synapses and ultimately cognitive dysfunction, according to a study in mice. Read More
Imaging technique reveals previously unseen nanostructures in brain tissue
Swellable hydrogels have enabled researchers to “decrowd” biomolecular structures in cells and tissues, revealing previously hidden nanostructures and providing imaging of the structure of Alzheimer’s-linked amyloid beta plaques in greater detail than has been possible before. Read More
Boosting neuron production offers viable treatment strategy for Alzheimer’s: mice study
A new study from University of Illinois Chicago researchers shows that boosting neurogenesis, the process by which new neurons are formed in the brain, increases the number of newly formed neurons involved in storing and retrieving memories in the hippocampus of mice with Alzheimer’s disease. Read More
Blood-brain barrier cells regulate neurons in fruit flies, suggesting role in neurodegeneration
Cells in the blood-brain barrier regulate nerve ensheathment and neurotransmitter release in fruit flies, suggesting they may play a role in neurological conditions in humans. Read More
Repurposed drug shows promise in animal studies as potential therapy for ALS
A drug used to treat enlarged prostates and high blood pressure could help to slow the progression of motor neuron disease, which is also known as amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder. Read More
Nanoparticles protect mice from blood vessel rupture, offers potential therapy for abdominal aortic aneurysms in humans
Administration of small interfering RNA nanoparticles has protected mice from sudden death due to the rupture of a major blood vessel in the abdomen, setting the stage for research that could ultimately enable treatment for people at risk of life-threatening abdominal aortic aneurysm. Read More
Conferences
BioProcess International (BPI) Conference
September 27-30
Boston, Massachusetts United States
Laboratory Products Association Annual Meeting
October 1-4
Scottsdale, Arizona United States
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
IDWeek 2022
October 19-23
District of Columbia United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter