CAR T-cell therapy collaborations expand cancer treatment options
Considering the broad range of the causes of cancer and the heavy impact on patients, advanced and innovative treatments are essential to fighting it. One technology being explored for this purpose is CAR T-cell therapy, because it trains the body's immune system to specifically target cancerous cells, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Some healthcare institutions are collaborating with companies to develop such technologies, including Celularity, Lonza, and the Memorial Sloan Kettering Cancer Center. Read More
Critical step identified in immune system response could lead to new treatments
New research has identified a crucial protein that controls the immune system's release of a key factor in fighting infections. The study, published in the journal Nature Communications on January 10, found that the MNDA protein is necessary for white blood cells to produce a type of interferon. This discovery could lead to new drugs to help fight infections or treat autoimmune conditions. Read More
How COVID-19 has shed light on importance of biotech tools, health equity
As the world enters the third year of the COVID-19 pandemic, it is clear that the virus has taught humanity some very tough lessons, but there have also been significant scientific advances. A panel explored the current challenges facing the industry, along with the silver linings, on January 10 at Biotech Showcase 2022. Read More
FDA authorizes Pfizer's COVID-19 pill
The U.S. Food and Drug Administration (FDA) has issued an emergency use authorization for nirmatrelvir and ritonavir tablets (which are co-packaged for oral use and sold under the brand name Paxlovid) for the treatment of mild to moderate COVID-19 in adults and pediatric patients (age 12 and older) who have tested positive for SARS-CoV-2 and who are at high risk of developing severe COVID-19, including hospitalization or death. Read More
COVID-19-related sales remain strong for lab tool firms in 2021
Laboratory tool companies have been among the biggest beneficiaries of U.S. government COVID-19-related spending on coronavirus testing and vaccine R&D and manufacturing. COVID-19-related sales have propelled sales at Thermo Fisher Scientific, Danaher, and PerkinElmer, already three of the world's largest scientific instrument and reagent providers. Read More
Gamma delta T cells may hold key to malaria immunity
Scientists have shown how a poorly understood group of immune cells -- gamma delta T cells -- are directly involved in immunity to malaria, according to research published December 1 in Science Translational Medicine. The results promise to spur the future development of next-generation malaria vaccines. Read More
Technology upgrades needed to address future pandemics, GAO report says
Vaccine R&D and manufacturing face many challenges despite the success of COVID-19 vaccines. This is according to a new U.S. Government Accountability Office (GAO) report. Read More
Where is the immunotherapy field headed after COVID-19?
WASHINGTON, DC - Best known for his contributions to the Moderna COVID-19 vaccine, former Moderna chief medical officer, Dr. Tal Zaks, PhD, chaired a session on RNA vaccines at the Society for Immunotherapy of Cancer's (SITC) 2021 annual meeting. Zaks shared his perspectives and hopeful outlook with ScienceBoard at the meeting. Read More
Online portal helps screen COVID-19 drug candidates
An interdisciplinary team of engineers and scientists has released DINC-COVID, a web-based portal where researchers can screen COVID-19 drug candidates that might attack specific SARS-CoV-2 proteins. Details of the new platform were published online in Computers in Biology and Medicine. Read More
The continued challenges of flavivirus serology
Flaviviruses are a genus of positive-sense RNA viruses, largely transmitted by mosquito and tick vectors that cause infections, including yellow fever, dengue, the Zika virus, West Nile virus, Japanese encephalitis, and tick-borne encephalitis. In fighting the emergence of flaviviruses, a well-established gap in our arsenal is the availability of accurate diagnostic data. Read More
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