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Reanalysis of old data reveals overlooked liver gene therapy vector with better properties
Rational design and directed evolution have created an adeno-associated virus (AAV) capsid that is better at targeting the liver, setting the stage for its use as a gene therapy vector.
Engineered stem cells clear barrier to potential one-time treatment of ALS
Researchers have used human induced pluripotent stem cells (iPSCs) to overcome a barrier to the supply of a potential treatment for amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa.
FDA approves cell therapy treatment for transplantation in blood cancer patients
The U.S. Food and Drug Administration (FDA) on Monday approved the product Omisirge, a cell therapy treatment, for transplantation in blood cancer patients. The phase III trial results, published October 21, 2021, in the journal
, found the efficacy of Omisirge transplantation superior to standard umbilical cord blood transplantation.
Dialing down activity of Cas enzyme improves safety of CRISPR gene editing in mice
Scientists have modified the synthetic guide RNA (gRNA) that enables CRISPR-Cas gene editing to make the process safer for use in humans.
Insights into how viruses assemble in cells unlock opportunities to improve gene therapy
Researchers have revealed how viral nucleic acids are packaged into particles in cells, generating insights that could improve the delivery of gene therapies and treatment of infectious diseases.
Research reveals possible gene therapies for polycystic kidney disease
Researchers have found that a small piece of a specific protein might be key to preventing autosomal dominant polycystic kidney disease. Their study, published March 30 in
, could lead to new gene therapies for treating the disease, the researcher said.
Riboswitches enable small molecules to regulate activity of anemia gene therapy in mice
Astellas Pharma has helped develop a system for using small molecules to regulate gene expression that could improve the safety of gene therapies.
A*STAR partners with startup to create diabetes cell therapies tailored to Asian patients
BetaLife has acquired the rights to human induced pluripotent stem cell (iPSC) technology from Singapore’s Agency for Science, Technology, and Research (A*STAR) for use in the treatment of diabetes.
Stem cell-loaded plug improves outcomes in hard-to-treat Crohn’s disease patients
Most Crohn’s disease patients experienced complete clinical healing of perianal fistulas after treatment with a stem cell-loaded plug, according to data published in the journal
Diseases of the Colon & Rectum
At SLAS 2023, companies showcase, launch advanced automation and screening technologies
At the Society for Laboratory Automation and Screening (SLAS) 2023 International Conference and Exhibition, being held in San Diego from February 25 to March 1, numerous firms have announced that they are showcasing emerging technologies for advanced life science applications.
More Conferences »»
Roche launches Institute of Human Biology for human model systems to advance research and drug development
Sophia Genetics partnering with Agilent Technologies to offer cancer analysis solution
Theratechnologies data suggests tesamorelin may improve metabolic profiles in people with HIV
Quanterix expands laboratory-developed-test menu with launch of neurofilament light chain test
Grail launches methylation-based liquid biopsy solution for cancer research in a post-diagnosis setting
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