Cancer & Disease Research
Demand for viral vectors seen outpacing capacity growth despite investment surge
The growth in demand for viral vectors is outpacing a push to add capacity, leading to predictions that the current supply shortage will continue despite investment in the space. Read More
New type of CAR T cells provide on-off switch to improve cell therapy safety, efficiency
Researchers at Boston University have created on and off switches for chimeric antigen receptor (CAR) T cells, enabling them to control the activity of therapies using an approved drug. Read More
Akadeum looks to advance the cell separation process with microbubbles
Microbubble technology offers researchers the ability to perform cell separation without a column or magnet, generating higher yield and faster turnaround times, according to Akadeum Life Sciences CEO Brandon McNaughton who spoke with ScienceBoard.net about the company's technology. Read More
CRISPR reveals way to enhance the function, persistence of CAR T-cell therapies
The use of CRISPR knockout screens have uncovered a new regulator of immunity that could enhance the function and persistence of anti-cancer T-cell therapies, according to a study published on August 24 in the journal Nature. Read More
Discovery of widespread DNA damage in stem cell lines spurs call for pre-use sequencing
More than 70% of stem cell lines derived from human skin cells have damage to their DNA that could compromise their use in research and cell-based therapies, according to a study published August 11 in Nature Genetics. Read More
Soluble BCMA acts as decoy receptor to curb blood cancers in mice: study
A soluble version of B-cell maturation antigen (BCMA), a B-cell surface receptor, may act as a decoy to stop two proteins driving the growth of blood cancers, according to a new study by researchers at Stanford University. Read More
ARM, NIIMBL offer best practices, standards for cell therapy manufacturing challenges
The Alliance for Regenerative Medicine (ARM) and the National Institute for Innovation in Manufacturing BioPharmaceuticals (NIIMBL) have released best practices and a standard methodology intended to assist the cell-based therapy field with its ongoing manufacturing challenges. Read More
3D imaging reveals picture of T-cell activity to unlock solid tumor opportunity
Researchers have used imaging and transcriptomics to identify T cells with potent serial killing capacity in a push to expand use of the immunotherapies to solid tumors. Read More
Analysis of nanoparticles, cancer cells could aid development of nanoparticle-based drugs
Researchers have identified biomarkers that predict whether different types of cancer cells will take up specific nanoparticles, potentially helping to overcome some obstacles to the development of nanoparticle-based drugs. Read More
New DNA editing tool could enable more personalized cell therapies
University of Minnesota, Twin Cities researchers have developed a new tool to predict and customize the rate of a type of DNA editing called site-specific recombination, offering the potential for more personalized cell therapies. Read More
Conferences
BioProcess International (BPI) Conference
September 27-30
Boston, Massachusetts United States
Laboratory Products Association Annual Meeting
October 1-4
Scottsdale, Arizona United States
Cell & Gene Meeting on the Mesa
October 11-13
Carlsbad, California United States
IDWeek 2022
October 19-23
District of Columbia United States
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