Lentiviral cell therapies hold promise for monogenic blood disorders
Lentiviral vectors show promise for monogenic blood disorders and the future is bright for these genetically modified cell therapies, according to Dr. Michel Sadelain, PhD, who discussed the topic during the George Stamatoyannopoulos Memorial Lecture at the annual meeting of the American Society of Gene & Cell Therapy. Read More
CRISPR gene editing adapted for white blood cells
An adapted version of the CRISPR-Cas9 gene editing technique opens up the ability to manipulate human monocytes -- white blood cells that play vital roles in the immune system. The new study, published in Cell Reports on May 11, shows that the cells function normally following gene editing, allowing biologists to better understand how the cells interact with diseases like HIV. Read More
AI tracks cell movements in stem cell colonies
Scientists are still trying to understand how stem cell clusters assemble to form complex organs. To help demystify this phenomenon, researchers developed an ensemble of cell-tracking algorithms to track the movements in colonies of human induced pluripotent stem cells. The research demonstrates the potential of artificial intelligence (AI) in developmental biology. Read More
Quantitative image analysis provides confidence in drug development
Olga Kubassova, PhD, CEO of Image Analysis Group, spoke with ScienceBoard.net about how computational analysis is improving clinical trial imaging. Read More
Potential of gene editing for clinical use highlighted at ASGCT 2021
From base editing to in vivo CRISPR therapeutics and CRISPR-modified bacteriophages, scientists discussed innovations in preclinical research that have allowed them to advance these unique products to the clinic during a scientific symposium at the 2021 American Society of Gene & Cell Therapy (ASGCT) virtual meeting. Read More
Nobel Prize winner Doudna shares perspectives on future of CRISPR gene editing
Small science can translate into big discoveries, according to Nobel Prize laureate Jennifer Doudna, PhD. She discussed how her curiosity in understanding CRISPR led to the gene editing revolution in a talk at the 2021 American Society of Gene & Cell Therapy virtual meeting. Read More
Life science microscopy techniques get AI upgrade
Artificial intelligence (AI) can be used to speed up the computationally intensive process of light-field microscopy, a 3D microscopic imaging method. Researchers who developed the technique refer to it as hybrid LFM (HyLFM) and described the method in a paper published on May 7 in Nature Methods. Read More
Preparation is key for postdocs to transition to industry positions
On-Demand Webinar -- Postdoctoral positions are a natural choice for many scientists who have just received their PhDs. Postdocs allow scientists to gain invaluable research experience and training under guided mentorship -- and potentially transition to industry jobs, explains Natalia Martin, PhD, a program manager at the American Chemical Society. Read More
Tiny mechanical forces can have a massive effect on T-cell activation
A new study reveals how tiny forces between T cells and their targets can help to jumpstart protective immune responses. Research published in Nature Communications on May 4 uses cutting edge microscopy techniques to track the association and dissociation between T cells and antigens. Read More
Hope for next-gen COVID-19 vaccines may rest in an unexpected region of the virus
Researchers further elucidated how antibodies produced in people who effectively fight off SARS-CoV-2 work to neutralize the part of the virus responsible for causing infection. The study, published in Science on May 4, describes how antibodies targeting sections of the virus outside of the receptor-binding domain may be useful in the development of vaccines and therapies. Read More
Conferences
Science Briefs
Member Rewards
Earn points for contributing to market research. Redeem your points for merchandise, travel, or even to help your favorite charity.
Research Topics
Interact with an engaged, global community of your peers who come together to discuss their work and opportunities.
Connect
